

💼 Stay itch-free, stay unstoppable — professional skin relief that works as hard as you do!
E45 Itch Relief Cream is a clinically proven, dual-action treatment formulated with 5% urea and 3% lauromacrogols to instantly soothe itching and skin irritation caused by eczema, dermatitis, and dry skin. This non-greasy, perfume-free cream hydrates deeply while calming sensitive skin, making it ideal for daily use on face, hands, and body. Trusted for over 60 years, E45 combines dermatological expertise with gentle care to keep your skin comfortable and protected.












| ASIN | B01BKO8B4G |
| ASIN | B01BKO8B4G |
| Best Sellers Rank | 1,014 in Health & Personal Care ( See Top 100 in Health & Personal Care ) 9 in Skin Condition Remedies 9 in Itching & Rash Treatments |
| Brand | E45 |
| Country of origin | United Kingdom |
| Customer Reviews | 4.5 4.5 out of 5 stars (1,811) |
| Customer reviews | 4.5 4.5 out of 5 stars (1,811) |
| Date First Available | 8 Feb. 2016 |
| Format | Cream |
| Item model number | 100694329 |
| Manufacturer | E45 |
| Manufacturer contact | MA holder: Crookes Healthcare Ltd, NG2 3AA, UK. Manufacturer: Reckitt Benckiser Healthcare (UK) Ltd, HU8 7DS. |
| Product Dimensions | 3.8 x 4.2 x 14.2 cm; 60 g |
| Storage Instructions | Store below 25°c. |
| Units | 50.0 Grams |
| Weight | 50 g |
A**L
Excellent
I have mild eczema, and try to steer clear of steroid creams after years of use. So I tried this product and found it to be great for mostursing and soothing some mild problem areas. Of course it's not as fast acting but it feels better for my skin. I love it.
P**D
Excellent product for itchy skin
Excellent, works very well on eczema
P**R
Really good but leaves a smell
It's very good at relieving my super sensitive, dry, itchy skin. It love that it doesn't leave my skin greasy or clammy feeling. The only thing I don't like is the smell. I'm not sure if that is typical of E45 or some other ingredient in this formulation.
S**.
E45 Itch Relief Cream.
Very good product, advised to get it by a local District Nurse for my Husbands as he felt itchy all the time due to ilness, he felt much better after rubbing it in the itchy areas. I will buy it again.
H**R
Cream
Very good for dry skin behind ear nose or side head
L**0
Last long
Best itch cream on the market it’s so soothing
T**D
E45 for itchy skin
Very good price this cream certainly eases itching in my cast my arm i personally need to use it 4 times a day right now
X**S
Fast absorbing cream for irritated skin
This cream spreads well and absorbs almost instantly, leaving the skin soft without any stickiness. It helps reduce that itchy, uncomfortable feeling and is gentle enough for frequent use. The 50 g size is convenient for carrying around.
O**A
It came in before the delivery date. I would recommend.
Trustpilot
3 weeks ago
1 month ago