

🐾 Stay ahead of pests with FRONTLINE Plus — because your big dog deserves big protection!
FRONTLINE Plus Flea and Tick Treatment for X-Large Dogs (89-132 lbs) offers a waterproof, fast-acting topical solution that kills fleas, flea eggs, larvae, chewing lice, and ticks for 30 days. Trusted by pet owners for over two decades, it uses a dual-action formula with fipronil and (S)-methoprene to break the flea life cycle. Easy to apply monthly, it continuously replenishes through sebaceous glands, ensuring lasting protection even if your dog gets wet.

















| ASIN | B0002J1FP8 |
| ASIN | B0002J1FP8 |
| Age Range Description | All Life Stages |
| Best Sellers Rank | #2,007 in Pet Supplies ( See Top 100 in Pet Supplies ) #12 in Dog Flea Drops |
| Brand Name | Frontline |
| Breed Recommendation | Large Breeds |
| Color | Red Box |
| Country of Origin | France |
| Customer Reviews | 4.4 4.4 out of 5 stars (15,144) |
| Date First Available | May 30, 2004 |
| Date First Available | May 30, 2004 |
| Department | Flea & Tick |
| Department | Flea & Tick |
| Directions | Directions for Use Step 1. To REMOVE Applicator: 1. Use scissors to separate one blister; 2. Use scissors to cut along dotted line; 3. Peel down foil to remove the applicator. Step 2. OPEN Applicator. Hold upright with foil side toward you and snap applicator tip. Step 3. APPLY FRONTLINE Plus. Part the dog’s hair between the shoulder blades. Place the applicator tip just above the skin and squeeze… |
| Included Components | Package includes 3 applicators |
| Is Discontinued By Manufacturer | No |
| Item Dimensions LxWxH | 5.75 x 0.75 x 4.5 inches |
| Item Package Dimensions L x W x H | 5.87 x 4.37 x 0.75 inches |
| Item Weight | 1.6 Ounces |
| Item model number | 72220 |
| Item model number | 72220 |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer recommended age | 1 month and up |
| Model Name | FRONTLINE Plus Extra Large Dog |
| Number of Items | 3 |
| Product Dimensions | 5.75 x 0.75 x 4.5 inches; 1.6 ounces |
| Size | 3 Count |
| Specific Uses for Product | Parasites |
| Style | 3 Count |
| Target Audience Keyword | dogs |
| Warranty Description | If you are not satisfied with FRONTLINE Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842 |
T**E
This stuff still works great
I bought this because I remember, this was the first thing that came out to kill fleas & ticks! I haven't seen any in years! I'm glad I found it on Amazon! Because I can't afford the other stuff & too! The other stuff I don't really trust it much! This is well worth the money, & has worked great on my 116 pound German shepherd, yup she could lose a few pounds. But she's not scratched for fleas.. she does have dry skin. There was no smell & always fell safe applying the tube opening it away from me & applying it between the shoulder's! So thankful they still make Frontline & it works! Am definitely going to be buying more!
S**H
Still works in my part of the state
Easy to apply if you can make a part in your dog's hair. I always get it on my hands and wash it off as soon as I am done with the dogs. Never a problem on my skin due to this timeliness I guess. Kills the ticks who settle down to bite and still works on fleas for me. Ten miles down the road, however, it does not work anymore. Life finds away...
S**.
Medicine
It help to keep the ticks and flees away from the dogs
D**S
Many uses- goat & swine mange, chicken mites, dogs.
Fantastic for feather and leg mites in chickens, scales start falling off within days, can take a few treatments for bad infestations. Slather with neem oil also to suffocate the mites between treatments. A lot of vets recommend this off label for mange in goats, swine and camelids and it works wonderfully. Treat, then treat again in 2-4 weeks. Hair starts growing back within a few days. In 2 weeks you can hardly tell but treat again or the mites come back since the eggs are hatching- get them on a mineral buffet as well so they can balance their systems and immunity to pests. However it is not lasting the 30 days it used to for fleas in dogs. Fleas were gone for about a week after treatment. Then one or 2 started appearing again. I am going to treat dogs for fleas every 2 weeks.This is the reason for 4 stars. I buy this plus size to treat 4 small 25lb dogs. It works great for chicken leg mites and feather mites, youtube videos show you how to apply, a drop on each leg, around vent, back of neck etc. Fantastic for mange in goats and llamas- use the same weight used for a dog.
M**Y
Don’t waste your time and money on this.
Didn’t work at all! Shouldn’t have wasted the time or money on this! Ended up having to go to my vet and buying a different product! From what I’ve been told frontline has been around so long fleas are resistant to it now. Wish I could get my money back on it. Just glad that after talking to my vet and getting a different product my pets are comfortable and doing well!
K**J
Best flea and tick med!
Arrived quickly. Always works so well for fleas and ticks for our 2 German Shepherds (very thick hair). We live on lots of land with woods so they come into contact with fleas/ticks, but when Frontline is used, we don’t have any problems. Love the bigger pack that is offered and at the best price!! Fleas: No fleas on our dogs! Ease of application: Just takes a few seconds to apply!
A**Y
Good product
Product works well, I live in Florida, off grid, in the woods. We have lots of sand, and my lab is active and always playing in the forest. I never have problems with ticks or fleas. Nats are still a pain, but I use Avons, Skin So Soft, I spray it on my hands, lightly pass over her eyes, back and tail. I've never seen skin or eye irritation from any of my dogs. From the flea control or the Skin so soft. Hope this helps.
5**0
WASTE OF MONEY DOESN'T WORK!!!!
Since application I have literally pulled off seven ticks. Some attached some crawling to attach. Literally pulled two off within 6 hours of application. The rest have been within the last week. We have Lyme disease here. This was the reason why I got this. If my dog ends up with Lyme disease you'll end up with a bill!! I want my money back. Don't listen to their money back. Guarantee you call that number on the back of the box and they just want to find all sorts of loopholes of reasons. Why not to give you your money back. They want ticks to eat on your dog up to 3 months! It doesn't matter where I purchased it. The facts are the facts. It does not work! seven ticks 3 weeks. Says "kills ticks including those that may transmit Lyme disease" when you talk to the company they say it doesn't protect against Lyme disease! Fair the definition of what's wrong with companies finding loopholes to basically screw over their customers.
Z**E
It says there is 6 doses inside but i received only 3 and package was opened!
Trustpilot
2 weeks ago
1 day ago