Nature Made SAM-e Complete 400 mg, SAM-e Supplement for Mood Support, Dietary Supplement, 36 Tablets, 36 Day Supply

I have an injury to my right hip joint. A small piece of bone is in my joint. There was a 50% chance that surgery would make it worse, so I didn't have a hip surgery. I heard someone praise SAM-e on Doctor Radio, so I bought the enterically coated brand that was mentioned along with some others. Nature Made SAM-e has stopped the pain. I take 2 of the tablets for best effectiveness. Studies have shown that joint comfort from SAM-e supplementation is best achieved at 600 to 1200 mgs. I don't use it for mood support which by the way would need a higher dose. I tried another brand that was on sale at Amazon, but after a month my hip pain was insufferable and had to take Aleve to do simple tasks. I started taking this brand of SAM-e again and in a few days the pain was gone so I didn't need Aleve.

Nature Made is the best SAM-e. Can never find it in Walgreens or Rite Aid anymore. Sucks because it was the only way it was affordable when it would be bogo. They don’t even sell the Walgreens or Rite Aid brands anymore I don’t get it. I bought naturemade religiously for over 20 years. I can’t afford it at this price but as long as the expiration date is like 2 years out and it’s fresh, they always made the best one. Enteric coated, empty stomach with B12, B6 & Folic acid. 1200-1600 mg a day for mood. 400-800 for joints and liver detoxification. Miracle supplement.

The effects are noticeable and positive. I accidentally bought this version and it was a good mistake because the pills are round and smaller (not small but smaller), making for easier swallowing compared to the lozenge shaped versions of SAM-e we used. However, the person taking it has difficulty swallowing pills so instead of buying this again we are trying a dissolvable brand of SAM-e. Would rather stick with Nature Made, but not until they do a melt one. If I could I'd give it 4.5 stars due to pill size.

Expensive. Packaged to take up a lot of room - I suppose to justify the prive. Works well.

Easy to take . More energy. Less depression. I stopped taking my Rx over time .. slowly. As it was making me feel sick. I tried this 30 days ago and this is my 2nd box. I feel the difference right away. Take first thing in the morning, empty stomach. I think if this is available I will use the rest of my life. Feel more positive. Helps my anxiety and my joints. I'm thankful.

This stuff works wonders! I went through a pretty rough patch in my life. I lost 2 dogs, 1 cat, and my best friend/roommate to cancer all within 2 years. My doctor placed me on Welbutrin but that stuff made me completely insane! 1 day I was angry, 1 day I was completely miserable, 1 day I was unbearably tired. I also had a horrible headache when I was taking it. I felt like was a mindless zombie on Welbutrin. I decided to stop taking the Welbutrin before it settled into my system. I figured I would try and go the more natural route after reading all the side effects of the other anti-depressant medications they have available. I first tried Kira St Johns Wort Tablets - 45 Tablets . These seemed to help, but it was very mild and not consistent in keeping my mood up. Then...there was Nature Made Sam-E. I tried some of the store brand Sam-E's to try and keep costs down, however, none of the other brands even came close to working as good as Nature's Made. And if you shop around you can usually find a buy one get one free at Walgreens, Giant, CVS, or even Amazon! This stuff helped me through the roughest time of my life. I've been using Sam-e well over 2 years now and if I even missed one dose I would immediately notice a huge change in my mood. I have been taking 1 400mg pill a day since I started. Once in a while I would take took 2 or 3 in a day. I just started taking 1 pill every other day to give my body a break because I do not like to be dependent on any type of medication. But for those super hard times, this stuff really helped to get me through. I highly recommend trying Sam-E. Especially before trying any prescription anti-depressants. It is a natural approach to overcoming depression, has low to no side effects at all (I never experienced any), and even if it does not help with improving your mental health, at least it is supporting your joints. ;) Hope this helps!

Helps with your pup’s liver function. Recommended by our vet and it really helps our elderly dog. Ask your vet about it!

My review on this needs a little backstory: I've been taking St. Johns Wort for several years for moderate depression and anxiety. It has changed my life; however, I began to worry about its counteractive effect on birth control. I don't want to use standard pharmaceuticals unless I absolutely have to, so I decided to try Sam-E. Effects of Sam-E on mood: Definite mood boost. Never sank into the very low spots that plagued me before. On energy: Insane energy levels. Useful, but a little scary. For several hours after I took it I was buzzing. On sleep: Gave me moderate insomnia. Again, I didn't feel tired, but not being able to sleep at night was frustrating. On urine?!: Bright highlighter yellow. Florescent pee. That was weird. On stomach: This is where it really got me. I took it after waking up, so empty stomach, and ate 40 minutes to an hour later. For the first week it gave me INTENSE stomach pain for about four hours after taking it. After that first week, the intense pain subsided to a dull ache, but - sorry for the graphics here - it gave me diarrhea every. single. day. Not so good. But since it worked so well at lifting my fatigue, I kept trying it, until week 5... On brain: When the dizziness set in. My brain started swirling around so vigorously I couldn't walk or drive. I actually kept taking it for a week after the dizziness started, because the mental clarity it had given me before was so useful. I didn't want the Sam-E to be the cause. But at week 6 I double checked the list of side effects for Sam-E and yes indeed, dizziness is on it. I switched back to St. Johns and in the weeks since the dizziness has slowly faded away. So, that was a long review, but I wanted to really share my experience. The upsides of Sam-E are very powerful, and since everyone's body reacts a bit differently, it's almost certainly worth a shot if you have anxiety, depression, and fatigue. If Sam-E doesn't work for you, I can recommend from my experience St. Johns Wort. It doesn't give the energy boost but it is a great mood balancer and has never messed with my stomach. I've also heard that 5-HTP can work well for some people, so you might give that a try too. I hope you find something that works for you! Just don't give up and assume that depressed is the only way you can be. As strange as it seems, taking a little plant pill or an enzyme really can be the thing that sets your brain right and gets you on a brighter path. It won't solve all your problems but it can help keep your mind from sabotaging you at every step. :) Good luck.