---
product_id: 3551976
title: "Nutramax Denamarin Liver Health Supplement for Large Dogs - With S-Adenosylmethionine (SAMe) and Silybin, 30Count(Pack of 1)"
brand: "nutramax laboratories"
price: "20387 kr"
currency: ISK
in_stock: true
reviews_count: 8
category: "Nutramax Laboratories"
url: https://www.desertcart.is/products/3551976-nutramax-denamarin-liver-health-supplement-for-large-dogs-with-s
store_origin: IS
region: Iceland
---

# 120mg Silybin complex Vet #1 recommended 425mg SAMe boost Nutramax Denamarin Liver Health Supplement for Large Dogs - With S-Adenosylmethionine (SAMe) and Silybin, 30Count(Pack of 1)

**Brand:** nutramax laboratories
**Price:** 20387 kr
**Availability:** ✅ In Stock

## Summary

> 🐾 Elevate your dog’s vitality with the liver supplement vets swear by!

## Quick Answers

- **What is this?** Nutramax Denamarin Liver Health Supplement for Large Dogs - With S-Adenosylmethionine (SAMe) and Silybin, 30Count(Pack of 1) by nutramax laboratories
- **How much does it cost?** 20387 kr with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.is](https://www.desertcart.is/products/3551976-nutramax-denamarin-liver-health-supplement-for-large-dogs-with-s)

## Best For

- nutramax laboratories enthusiasts

## Why This Product

- Trusted nutramax laboratories brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Trusted by Vets:** Nutramax is the #1 veterinarian recommended liver supplement brand for dogs.
- • **Powerful Liver Detox:** 425mg S-Adenosylmethionine fuels antioxidant glutathione for optimal liver cleansing.
- • **Clinically Backed & Safe:** Veterinarian-formulated with 30+ years of expertise, proven safe for dogs of all sizes.
- • **Superior Absorption Formula:** 120mg Silybin-phosphatidylcholine complex ensures maximum bioavailability over standard milk thistle.
- • **Supports Vital Organ Health:** Enhances liver’s role in toxin removal, energy storage, digestion, and immune defense.

## Overview

Nutramax Denamarin is a premium liver health supplement for large dogs, combining 425mg of S-Adenosylmethionine (SAMe) and 120mg of highly absorbable Silybin complex. Backed by over 30 years of veterinary science and trusted as the #1 vet-recommended brand, Denamarin supports liver detoxification, immune function, and overall vitality—helping your dog live a healthier, more active life.

## Description

Denamarin coated tablets containing SAMe (s-adenosylmethionine) and silybin can be used in dogs of all sizes to help support healthy liver functions. In addition, research has shown the administration of Denamarin coated tablets to be safe for dogs. Denamarin Liver Health Supplements are brought to you by Nutramax Laboratories Veterinary Sciences, the #1 veterinarian recommended supplement company. *Source: Survey conducted among small animal veterinarians who recommended animal supplements.

Review: Excellent Treatment for Older Fur-Kids With Liver Issues. - I foster dogs, but have chosen to specialize in the older and sicker rescued dogs. I have had many, many dogs with liver problems. But for a long time we were losing our precious furry friends, it was awful, there just was not really a very good treatment out there for an old dog with bad liver readings. The problem was that the old dogs all had arthritis, many had been brutalized and abandoned by previous owners, and there were some things that could not be fixed. However, finally we had access to a wide canine assortment of NSAID's. This was wonderful, the previous only hope was aspirin, with many associated bleeding risks, or dangerous steroids for their poor inflamed, badly healed, and otherwise painful limbs. They were always so good, even though I knew that they were suffering. Then, we suddenly had access to the wonderful mom-steroidal pain relievers. This was magic stuff. Dogs that could barely walk were bouncing around, dogs that could not climb stairs were bounding up, two steps at a time. However, there was a dark side to all of this joy...as we soon discovered. These miracle NSAID's were pretty rough on the livers of the old dogs. So much so that I was faced with the awful choice of continuing that medication, knowing that it was destroying their liver, but it was also keeping the dogs joints pain-free. My other alternative was no good alternative - no NSAIDS, just heavier and heavier doses of narcotics for the pain......helplessly watching the failing test results of my poor old pups. I lost quite a few that way, it almost killed me. Then Denamarin, and Marin came along. I use both on my old pups and it is another miraculous thing to witness. This is a nom-prescription item that magically lowered bad liver numbers, sometimes within a three or four week period.. It is very expensive, but desertcart has the best price of all. My dogs are living now, and not teetering on the edge with failing livers. It is possible to use NSAID's in conjunction with Denemarin, and the liver numbers are far better, and the dogs are not doped-up on narcotics, but can enjoy their last days. I am amazed by the breakthroughs that I have witnessed in the veterinary world over the last ten years that I have been fostering. Sometimes it is pretty magical, old dogs frolicking around my ankles each morning, demanding a treat, just like a bunch of pups. I am not a vet., I wish to make that crystal clea. I have no connection whatsoever with this company, indeed had never heard of them before my vet mentioned this drug. All that I can say is that I have had dogs my entire life, and I have witnessed far too many agonizing decisions that have had to be made. Watching an agonized old dog, painfully hobble around, or give the drug that will help with the arthritis...and have very negative effects with their livers. In the.end, we usually just tried to keep them out of pain, but they had.no good quality of life. Again, to be perfectly clear, with MY old dogs, under MY care, eating the very best of dog kibble, no fatty treats, no people food, and someone around at all times to give the drugs at the appropriate times, I have seen rapidly discernible improvement in my older guys. Not every dog reacts the same way, doses can be tricky, and.require a lot of blood testing' and fiddling with dosages, my dogs have definitely improved. Not all have a glorious outcome. But If they are willing to get out of their beds, and follow me to the kitchen to beg for food, my heart is happy. When you are working with old, injured, and sick dogs...little things matter a lot. Denemarin, along with another supplement : Marin, have made the lives of some of the older fur kids better, and happier. This will not save your old dog, there will be heart problems, cancers, and other issues upon which Denemarin has no effect. But for the dogs in the specific conditions that I have outlined, I have seen a definite difference in both the quality of life for the dog, as well as better liver readings on their blood tests. Again, it is expensive, this makes for a very hard decision for every pet lover. But, it is effective on many dogs. And that is a miracle for me. We are saving dogs that we would have lost ten years ago, and this supplement has had a lot to do with that. It is up to the pet owner, but under the conditions that I have stipulated, this is a worthwhile addition to the supplemental diet of old dogs.
Review: Quality supplement for better digestion and quality of life for my dog. - My dog has been having liver issues and has been showing high levels of enzymes on his tests. He's about 8 years old right now and I want to make sure he's getting good care. The doc recommended a couple of types of supplements to help with those high liver enzymes and I chose the Denamarin based on reviews. So, far everything seems to be going well. My dog seems to be able to tolerate it well. He has a sensitive stomach and often throws medicine back up. He hasn't done that yet with the Denamarin. Even more positive is that his first test has come back showing decreased levels of those enzymes, so I guess it's working and doing what it's supposed to do. The price seems to be a little spendy to me for a non-prescription supplement, but it's the best one I can find and it seems to be working. What are you going to do? My dog's worth it, so he's going to get it.

## Features

- Liver Support for Dogs: Denamarin is the #1 veterinarian recommended liver support supplement for dogs. This supplement contains s-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione - one of the liver’s main detoxifying agents
- High-Quality Ingredients: The Silybin found in Denamarin has shown better absorption by dogs than the standardized milk thistle extract found in many other products
- Support Your Dog's Liver Health: The liver is one of the most vital organs in your pet and is responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system
- From the #1 Veterinarian Recommended Supplement Company*: Nutramax Laboratories Veterinary Sciences has been a leader in pet health for over 30 years, and provides supplements to support joint health, digestive health, and overall wellness
- Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to ensure your pet is receiving a safe supplement

## Technical Specifications

| Specification | Value |
|---------------|-------|
| Active Ingredients | S-Adenosylmethionine 425 mg, Silybin-phosphatidylcholine complex (SPC)* 120 mg, *Providing 35 mg of Silybin A+B Active Ingredients S-Adenosylmethionine 425 mg, Silybin-phosphatidylcholine complex (SPC)* 120 mg, *Providing 35 mg of Silybin A+B See more |
| Brand | Nutramax Laboratories |
| Customer Reviews | 4.6 out of 5 stars 3,597 Reviews |
| Flavor | Liver |
| Item Form | Tablet |
| Item Weight | 1.6 Ounces |
| Product Benefits | Immune Support |

## Product Details

- **Brand:** Nutramax Laboratories
- **Flavor:** Liver
- **Item Form:** Tablet
- **Item Weight:** 1.6 Ounces

## Images

![Nutramax Denamarin Liver Health Supplement for Large Dogs - With S-Adenosylmethionine (SAMe) and Silybin, 30Count(Pack of 1) - Image 1](https://m.media-amazon.com/images/I/61tmHA5XDlL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: I know it says to give on an empty stomach, but is it ok to hide the pill in a small piece of food? Not sure my dog would eat just the pill.**
A: Yes! The packaging says “tablets should be given on an empty stomach; however, if needed they can be administered with a small amount of food or treat.” (The reason I took my Sheltie to the vet in the first place was because he suddenly stopped eating. After tests, my dog was prescribed this medication for his liver problems. But how do you feed pills to a dog that won’t eat anything, not even his treats or cheese? Well, the vet opened a can of pate’ CAT FOOD and surprisingly my dog ate it! The vet said cat food is normally too fatty to be healthy for dogs but they’ll eat it -even when they won’t eat anything else-because it’s like a super-juicy hamburger to them! The vet suggested putting the pill in a small ball of canned pate’ cat food, especially if your dog has no appetite. First, give a tiny ball of pate’ without a pill so they anticipate the flavor then give them a ball with the pill hidden in it while showing them there is more- tricking them into gulping down the pill-ball. Follow up with a tiny dab of cat food and you’re done for an hour when they can stop fasting and eat a meal. In my dog’s case, the meal was cat food pate’ for a few days, then soft-ish dog food smeared with cat food pate’, and now we just use the cat food to hide pills in.) Sorry for the long answer, hope it helps someone.

**Q: How large are the pills? I have a cat w/ liver failure & the pills from the vet are HUGE. Looking for an alternative asap. Thank You! :)**
A: I give one for my 11 lbs. poodle which is the small one and a larger one for my 22 lbs. poodle.  I gave up on the trauma of cramming it down their throat with a pill dispenser.  I know direction say on an empty stomach; however, it is important they take the pills so I bought some human liver pate over in the deli meat section and I give the a tiny treat to trick them...about the size of a ballpoint pen end and then I wrap the pill in just enough liver that they wolf it down and then I give them that tiny bit to follow up.  I know it sounds crazy but I watched a vet on youtube show how and it worked.  The first little bit programs them for the larger piece which only covers the pill...they wolf it right down.  I know it is working because the 22lbs. liver was so high it wouldn't even register on the scale.  Follow up last week the liver blood work showed a dramatic drop to well below 300.  Hope that helps.

**Q: Has anyones dog had any adverse reactions to this product? Ours did.**
A: My dog had diarrhea, but it was from a change to raw food, not Denamarin.  Once he had transitioned to entirely raw, diarrhea for two days straight.  Once he was back on his canned food, he was fine, with normal poop.  The real positives are that he has perked up, that he is hungry, and that some of the side effects from Adrenal Cushing's have improved: less water drinking, hair growing in thicker, less of a pot belly, and skin lesions have decreased.  I am happy that he is improving and will continue with this.

**Q: Nutramax claims this product does not require a persciption (a dietary suppliment) but is only sold to licenseed vets?**
A: No it is not only sold to vets, because my vet told me to go to Amazon to order this product

## Customer Reviews

### ⭐⭐⭐⭐⭐ Excellent Treatment for Older Fur-Kids With Liver Issues.
*by H***R on April 19, 2016*

I foster dogs, but have chosen to specialize in the older and sicker rescued dogs. I have had many, many dogs with liver problems. But for a long time we were losing our precious furry friends, it was awful, there just was not really a very good treatment out there for an old dog with bad liver readings. The problem was that the old dogs all had arthritis, many had been brutalized and abandoned by previous owners, and there were some things that could not be fixed. However, finally we had access to a wide canine assortment of NSAID's. This was wonderful, the previous only hope was aspirin, with many associated bleeding risks, or dangerous steroids for their poor inflamed, badly healed, and otherwise painful limbs. They were always so good, even though I knew that they were suffering. Then, we suddenly had access to the wonderful mom-steroidal pain relievers. This was magic stuff. Dogs that could barely walk were bouncing around, dogs that could not climb stairs were bounding up, two steps at a time. However, there was a dark side to all of this joy...as we soon discovered. These miracle NSAID's were pretty rough on the livers of the old dogs. So much so that I was faced with the awful choice of continuing that medication, knowing that it was destroying their liver, but it was also keeping the dogs joints pain-free. My other alternative was no good alternative - no NSAIDS, just heavier and heavier doses of narcotics for the pain......helplessly watching the failing test results of my poor old pups. I lost quite a few that way, it almost killed me. Then Denamarin, and Marin came along. I use both on my old pups and it is another miraculous thing to witness. This is a nom-prescription item that magically lowered bad liver numbers, sometimes within a three or four week period.. It is very expensive, but Amazon has the best price of all. My dogs are living now, and not teetering on the edge with failing livers. It is possible to use NSAID's in conjunction with Denemarin, and the liver numbers are far better, and the dogs are not doped-up on narcotics, but can enjoy their last days. I am amazed by the breakthroughs that I have witnessed in the veterinary world over the last ten years that I have been fostering. Sometimes it is pretty magical, old dogs frolicking around my ankles each morning, demanding a treat, just like a bunch of pups. I am not a vet., I wish to make that crystal clea. I have no connection whatsoever with this company, indeed had never heard of them before my vet mentioned this drug. All that I can say is that I have had dogs my entire life, and I have witnessed far too many agonizing decisions that have had to be made. Watching an agonized old dog, painfully hobble around, or give the drug that will help with the arthritis...and have very negative effects with their livers. In the.end, we usually just tried to keep them out of pain, but they had.no good quality of life. Again, to be perfectly clear, with MY old dogs, under MY care, eating the very best of dog kibble, no fatty treats, no people food, and someone around at all times to give the drugs at the appropriate times, I have seen rapidly discernible improvement in my older guys. Not every dog reacts the same way, doses can be tricky, and.require a lot of blood testing' and fiddling with dosages, my dogs have definitely improved. Not all have a glorious outcome. But If they are willing to get out of their beds, and follow me to the kitchen to beg for food, my heart is happy. When you are working with old, injured, and sick dogs...little things matter a lot. Denemarin, along with another supplement : Marin, have made the lives of some of the older fur kids better, and happier. This will not save your old dog, there will be heart problems, cancers, and other issues upon which Denemarin has no effect. But for the dogs in the specific conditions that I have outlined, I have seen a definite difference in both the quality of life for the dog, as well as better liver readings on their blood tests. Again, it is expensive, this makes for a very hard decision for every pet lover. But, it is effective on many dogs. And that is a miracle for me. We are saving dogs that we would have lost ten years ago, and this supplement has had a lot to do with that. It is up to the pet owner, but under the conditions that I have stipulated, this is a worthwhile addition to the supplemental diet of old dogs.

### ⭐⭐⭐⭐⭐ Quality supplement for better digestion and quality of life for my dog.
*by G***N on December 16, 2025*

My dog has been having liver issues and has been showing high levels of enzymes on his tests. He's about 8 years old right now and I want to make sure he's getting good care. The doc recommended a couple of types of supplements to help with those high liver enzymes and I chose the Denamarin based on reviews. So, far everything seems to be going well. My dog seems to be able to tolerate it well. He has a sensitive stomach and often throws medicine back up. He hasn't done that yet with the Denamarin. Even more positive is that his first test has come back showing decreased levels of those enzymes, so I guess it's working and doing what it's supposed to do. The price seems to be a little spendy to me for a non-prescription supplement, but it's the best one I can find and it seems to be working. What are you going to do? My dog's worth it, so he's going to get it.

### ⭐⭐⭐⭐⭐ Saved My Dog's Life
*by H***. on May 24, 2015*

I can't say enough great things about Denamarin. In August 2014, I had a feeling I should have the vet run blood work on my 11 year old lab mix. She was acting fine, and had no real health issues, it was just a nagging feeling. We ran the blood panel, and it was a good thing we did. ALT is a liver enzyme that is released when there is damage occurring to the liver. A normal ALT value is ideally below 110, my dog's was 390. Not good, that meant there was some serious liver damage happening. We ran a lot of tests to see what the cause could be. Ultrasound showed nothing abnormal. We did a few rounds of antibiotics in case it was some sort of hepatitis. Nothing really made a difference, and we couldn't see what the issue was. So we started her on Denamarin. I really didn't think it would do too much, but I was willing to try. Slowly her ALT values began to lower, I'll post a little table at the bottom so you can see. By October her ALT was down to 147! Then in November we ran out of Denamarin for a couple weeks. Honestly, I wasn't too concerned. I assumed she was just getting over whatever had been the issue, I didn't think the key to her improving was the Denamarin. The next time we measured her ALT in December it was back up to 243. We never ran out of Denamarin again after that, and as of May 2015 her ALT value was 46! Thats right, from a high of 390, down to 46. I could not be happier. Given her age, I did not think that we would be back in the normal range for much. But not only is her ALT back to normal, but so is every blood value they tested. This has been worth every penny. Helpful tip: it is probably a lot cheaper on Amazon than thru the vet. I save $20 a box here. --ALT Values on Denamarin-- Aug 2014 390 Sept 2014 290 Oct 2014 147 Dec 2014 243 (this is when we ran out of Denamarin) Jan 2015 114 May 2015 46

## Frequently Bought Together

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*Product available on Desertcart Iceland*
*Store origin: IS*
*Last updated: 2026-03-05*