




💨 Breathe Better, Live Sharper — The Enzyme Edge You Can’t Miss!
Doctor's Best Serrapeptase offers a high-potency 40,000 SPU proteolytic enzyme designed to support healthy sinus and respiratory function. Featuring advanced Serrateric coating technology, it ensures optimal absorption by protecting the enzyme from stomach acid. This vegan, non-GMO, and gluten-free formula helps break down protein buildup that can cause sinus discomfort, making it an essential daily supplement for proactive respiratory wellness.







| ASIN | B000EDCJ3Y |
| ASIN | B000EDCJ3Y |
| Age Range Description | Adult |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #30,482 in Health ( See Top 100 in Health ) #123 in Enzyme Nutritional Supplements |
| Brand Name | Doctor's Best |
| Color | No Color |
| Container Type | Bottle |
| Customer Reviews | 4.4 4.4 out of 5 stars (4,643) |
| Customer reviews | 4.4 4.4 out of 5 stars (4,643) |
| Diet Type | Vegan |
| Dosage Form | Capsule |
| Flavor | Unflavored |
| Global Trade Identification Number | 00753950001497 |
| Is Discontinued By Manufacturer | No |
| Item Dimensions | 5.4 x 5.4 x 9.4 centimeters |
| Item Form | Capsule |
| Item Weight | 106 g |
| Item model number | DRB-00149 |
| Manufacturer | Doctor’s Best, Inc |
| Manufacturer | Doctor’s Best, Inc |
| Manufacturer Part Number | DRB-00149 |
| Material Features | Vegetarian |
| Material Type Free | en_AE |
| Model Name | Serrapeptase, Non-GMO, Gluten Free, Vegan, Supports Healthy Sinuses, 40,000 SPU |
| Model Number | DRB-00149 |
| Number of Items | 1 |
| Primary Supplement Type | protein |
| Product Benefits | Healthy Sinuses |
| Product Dimensions | 5.41 x 5.41 x 9.37 cm; 105.69 g |
| Special Ingredients | Serrapeptase Enzyme (from Serratio sp.) 40,000 SPU |
| Specific Uses For Product | Healthy Sinuses |
| Total Servings Per Container | 90 |
| UPC | 753950001497 |
| Unit Count | 90 Count |
L**T
Most needed enzyme ...
Serrapeptase is one of the most needed enzyme by the body . It's not a digestive enzyme , it's a systemic enzyme , it breaks down foreign protein build up in the body ..i am using it for my mast cell issue , which is triggered by sour and cold foods and gives me very bad headache ( piercing pain on the top or side of head, behind the eyeballs ) i am feeling some relief , i used it for one month only. Hoping to continue for atleast 3 months to see the effect. I have noticed more energy with it especially when i keep fasting for longer after eating it. It increases blood flow also so it can help with hair loss too.
G**E
good
good so far, been taking this supplement for only 2 months , i have allergic rhinitis and i don't sneeze that much now.
B**Y
Allergic reaction
I buy so many Doctor's best product and these were good for me . I saw so many good reviews but this one did not suit me though .I had an episode of itching followed by lots of body pain with the first dose .Stopped taking it .Start small , may not be for everyone .
V**T
This is saving my life. After 20 days, I have slowly raised the daily dose to 120,000 SPUs. That's as high as I'll go. So far it has begun to cure senior moments, sharp pains in my temples, and pain from osteoarthritis. I can now stand for longer without pain, and I can bend enough so that I can watch the stars while standing up. Symptoms of dementia and Parkinson's and Alzheimer's are all getting less and less frequent. Even my vertigo upon moving from my left side to my right side in bed is going away. Floaters in my right eye are a tiny bit better but I'll have to continue therapy for 6 months to really see if it eats up floaters. I have experienced NO side effect at all but I should mention that I take NO drugs, medications, ibuprofen, antacids, at all -- zero. I drink ONLY filtered water. I eat no gluten. I eat no meat. I eat no cheese. My digestive system is clear and clean. If yours is not, you might want to make it so before starting on these. This stuff has been WONDERFUL for my skin too. I used to have a bunch of pin-prick sores on my arms but no more and my skin feels like silk now. My face is clearing up. I can breathe through my nose for the first time in my memory. My sinuses are healthy, and I can better tolerate allergens like wood smoke and pollen. When I sneeze now, it feels good instead of painful. I no longer do mouth breathing so I wake up without dry mouth. I can see better now that the film that would form in my eyes overnight is lessened. The confusion I would sometimes experience that made me think I might be getting Alzheimer's is gone. And the mild symptoms that made me think I was getting Parkinson's have lessened. My little finger on my right hand that has osteoarthritis no longer hurts when I bend it back to stretch it. I can stand up straight again which means that I can stand and walk for longer distances before I have to sit down in my wheetchair. I fully believe that in 6 months time, I'll no longer need a wheelchair. I started with one 40,000 SPU pill on an empty stomach each day. I did that for about a week and then moved up to 2 pills at the same time every day for about a week. Then I moved to one 120,000 SPU pill a day and that will be my dose for 6 months. Then I'll move back down to one 40,000 SPU pill per day for maintenance. I have had ZERO side effects so far and tiny little improvements that are growing day by day. I fully believe that it is helping me cure every single beginning disorder that has to do with plaques: Alzheimer's, Parkinson's, heart disease, mini strokes, osteoarthritis, joint issues, vertigo, arteriosclerosis, breast cysts, and breathing issues. This is a miracle for me. I wish it would work this well for everyone. Please note that I do not smoke. I do not drink alcohol. I do not take ANY drugs or medications or prescription meds of any kind. I do not do recreational drugs. I do not eat meat or cheese or milk. I drink ONLY filtered water that is free of heavy metals. I do not take multi-vitamins. I take only a few supplements and I take them with my major meal at the end of the day while I take my pill on an empty stomach in the morning. I eat only potatoes, peas, powdered butter, apples, and other fruits and veggies some time. I also eat a lot of milk chocolate almond bars (my one vice). I do not eat any gluten. Most of the fruits and veggies I eat are organic and those that are not organic are GMO free. I drink about a gallon of filtered water every day. I sleep better now for fewer hours and get up fewer times during the night to pee since I've been taking the serrapeptase. I have great dreams. I am almost 70 years old and now that I've found serrapeptase, I can see myself living well past 100 years old. I wish others could take this supplement. Maybe they get the bad side effects because of other lifestyle choices that do not match my lifestyle choices? I don't know. I only know that this stuff is saving my life and saving my independence. I feel YOUNG again. I still have quite a ways to go before I can give up my wheelchair, but I fully believe I will get there before Winter starts in Nov 2017. I'll update this review then to tell you how I've done and whether I am out of my wheelchair for good. I have family members who died from Alzheimer's or Parkinson's or artery blockages (heart attacks or strokes), or respiratory issues. Now I have a way to make sure that I never get those issues and it costs just 13 cents a day.
C**T
Works well for me, reduced my airway inflammation and solved my sinus problem.
P**H
I believe in homeopathic medicine along with conventional care but didn't think anything like this could touch the pain I was experiencing. I have SERIOUS back and neck pain from years of arthritis (RA and osteo) and degenerative disc disease. I can actually feel that "thick" feeling from inflammation along my entire spinal column as nerves get pinched and severe pain sets in. Anything can aggravate the inflammation from a change in barometric pressure to riding in the car and hitting a bump in the road the wrong way. I was beginning to think I was really going to have ask for narcotic pain killers which I've been dead set against for many reasons but sometimes the pain was becoming too much to tolerate. As soon as the bottle of this stuff arrived I took one because I was having a really bad day. Within an hour I suddenly realized my pain was decreasing. There was no way it could be from taking one Serrapeptase. Within 4 hours or so the pain got worse so I took another one and within a short time I started feeling less pain again. I can't believe it. This stuff really works for me. I'm not totally pain free. That would be too much to expect after all these years and so much damage BUT I do feel a significant difference. This pain I can live with and function with. I try to take Serrapeptase an hour before eating 2 or 3 times a day. Last night I slept well for the first time in almost a year. I didn't wake up in the middle of the night with pain and tingling in my arms and hands. I didn't have to try to sleep sitting up so nerves didn't get pinched. I slept like a normal person. I also have been dealing with neuropathy in both feet and legs up to my knees. Tonight, for the first time in months, I sat in my chair and watched TV for several hours without going nuts. This is starting to sound like an advertisement but darn....this stuff REALLY MAKES A DIFFERENCE!!!! It's been less than a week since I started this. I guess it's like taking a pain medication. It works quickly. I don't know everything about this supplement so I can't say one way or the other. I just know what's going on with me. If anything changes...if it stops working...if I start having any side effects or problems, I'll come back and update this review. I'm so happy I found out about this stuff. My husband is starting to take it too so we'll see how he does on it. I just signed up for Subscribe and Save for the 250 size bottle. I get a 15% savings because I get more than 5 Subscribe and Save items a month. That's a big savings....$5 a bottle off. I'm still trying to wrap my head around the results from the product but I guess I have to say I'm a believer...still a little skeptical that I'll continue to have such profound results without any problems but I'm sure going to keep taking it until there's a reason not to. This is just too good to be true and I'm so grateful. August 30th: My husband says he's having less back pain since starting Serrapeptase. He said he's also found information about it being helpful in keeping your arteries clear. Don't take that as a get out of jail card and permission to abuse your diet but it might be part of a heart healthy regime. My only problem with this supplement is none of my doctors seem to know what it is and look at me crossed eyed when I mention it. There's not a huge amount of information on the web from reliable sources so I feel like I'm flying a little solo when it comes to issues such as how to take it with other supplements and medications. I even called Doctor's Best and they basically told me they didn't have any information and I'm on my own. Really.....that from the supplier????
K**T
This review is about Serrapeptase AND Nattokinase since I started taking them both at the same time. Also, I'm not Ann, I'm her husband Kent. Ann passed away well over a year ago from cancer and the account was in her name so I decided to keep it that way. My back ground is that I had a mini stroke in April of 2011, about 2 & 1/2 years ago. At the time of the stroke I underwent tests and they found that I had a 90% blockage in my left carotid artery and a 20% blockage in my right. I underwent an operation to clean the plaque out of the left side, however the Dr. didn't touch the right side because of the small blockage. Ever since the stroke I've been walking around like I've been off kilter, almost dizzy all of the time, probably like vertigo. I was fine while sitting, however when I'd walk it was terrible. I refused to use a walker. Pride I guess. The day I came home from the hospital I used it to get into the house but as soon as I got in I folded it up and put it in the closet. I figured if I kept using it I'd use it forever. I go to the Dr. every 3 months for a check up and blood work. The last time, about 1 & 1/2 months ago she didn't like what she was hearing on my right side so she sent me for a sonogram on my carotid arteries. I went back to the testing place a few days later to pick up a copy of my report to see what it said and I sat there in total shock after I read it. My left side, where I had the operation was completely clear...GREAT! The right side that had the 20% blockage 2 &1/2 years ago...TOTAL OCCLUSION!!! Which means completely blocked. Even though my blood work has been great for the past 2 & 1/2 years, cholesterol and triglycerides have been great plus I eat healthy most of the time I was still blocked 100%. Go figure! For the next 2 days I sat in front of my computer researching what could be done if anything. I found that an operation is usually NOT done on someone with a 100% blockage. UCLA is just starting to do an experimental procedure but NO thanks! Also, there don't seem to be any offerings from the drug companies for anything related to this. Everything I read kept mentioning Serrapeptase and Nattokinase. I must have read at least 400 different testimonials on different sites across the web about how these relieve pain and seem to do other wonders PLUS they clean out arteries. Of course the testimonials I was most interested in were the ones where people had blockages in their arteries and the blockages had been greatly reduced by using this combination of Serra & Natto. I started taking the Serra & Natto about 5 weeks ago. I use Dr's Best for both. I take 6 - 40,000 SPU caps of Serra twice a day on an empty stomach along with 2 - 2000 FU caps of Natto twice a day. Here's what's happened so far: I noticed the arthritis pain in my knees and hips completely gone by the 2nd day. I can walk on the treadmill again for about 1/2 hour. YAY!!! Now this is the best part...for the last 3 days my dizziness has been gone. I can walk a straight line again! WOOO HOOO!!! Honestly, if the police had pulled me over and given me a sobriety test to where I had to walk a straight line...HA! They would have locked me up and thrown away the key figuring I was drunk as a skunk! And I DON'T drink! In 6 months or so I'm going to try and talk my Dr. into sending me back for another sonogram on those carotid arteries. Since I have a 100% blockage I'm not sure if the Serra and Natto will work. I never did read a testimonial from anyone that had a 100% blockage. I can only hope and pray. :-)
J**B
I've been waiting to leave a review regarding this product, but I decided to go ahead and give my thoughts about it thus far. I am prone to both keloid and hypertrophic scarring. Basically, my body doesn't know when to stop healing its wounds, and keeps compounding gross, ugly, red/purple scar tissue onto my skin. A couple years ago I had a stomach surgery, and two of my scars healed hypertrophicly. They've always bothered me. When I heard serrapeptase ate scar tissue, I decided to give it a try. In addition to the scars on my stomach, I have two small ones on my legs, and two very old keloids (around 15 years old) on my shoulder. My shoulder keloids are the most obvious. I don't wear belly shirts, so no one ever sees my abdominal scars, but I do wear sleeveless shirts, so my shoulder scars are pretty hard to miss. I've had them for so long that I'm used to them at this point, and I never really pay much attention to them. But about a week after taking the serrapeptase, I was hanging out with one of my friends, when he said "your shoulder scars look better." Shocked, I said really? He said "Yeah, they're flatter and not as red as they used to be." I hadn't told anyone that I was taking serrapeptase or trying to heal my scars. Additionally, when I got home after being away for 8 months (I had been taking serrapeptase for about a month at this point), my mom, dad, and granny all separately commented on how much better my shoulder scars looked and asked what I was doing for them. And I must say, they do look flatter and are starting to blend into my shoulder more. My stomach scars are also showing marginal improvement. While still discolored, they seem to be flattening and softening. And two small, hypertrophic scars on my legs also appear to be improving. They're shrinking a bit, and are a little flatter. I've been taking one pill a day for close to two months now. Miracles? Absolutely not. But there ARE NO miracles for these types of scars. Anyone who suffers from this type of scarring knows what I mean. Once you get them, you're out of luck. But this enzyme is giving me hope. Before, I thought the best I could do was try to prevent new scars from developing, but thanks to serrapeptase, I'm starting to think that maybe my old scars can be improved. If you suffer from keloid or hypertrophic scarring, I strongly recommend you invest in these. Don't expect an overnight cure, but I can attest to slow and steady improvement. *Note* I also want to mention that in addition to taking serrapeptase for my scars, I am also taking a garlic supplement, a bromelain supplement, and a turmeric supplement. I am working toward eliminating simple carbs and sugars from my diet (as they trigger inflammation), and I am trying to eat a predominantly plant based diet. I have done an immense amount of research into the mechanisms that cause our bodies to keloid. The key thing I've found is that these scars form due to an increased amount of inflammation. There is a nuclear protein that triggers the formation of the scars, and this protein is released when we have inflammation. Additionally, research has found that keloid tissue seems to have chronic inflammation. Garlic, bromelain, and turmeric have all been shown in scientific studies to reduce inflammation and repress the NF-KB protein that causes scar (and tumor) formation. I had been taking these other supplements before starting the serrapeptase, and I had not seen a noticeable difference in my already existing scars. I didn't get noteworthy scar improvement until I started the serrapeptase. HOWEVER, I wanted to provide this additional information, because I know how frustrating and hopeless you can feel when you have keloids. I know how scary it is when you have to go in for surgery or you get an injury and you know that it could morph into a grotesque, ever-worsening, never-improving scar. That is why I have spent hours upon hours reading scientific research studies that try to determine the mechanisms that causes this. I would recommend the additional supplements and dietary changes as well, as a preventative measure against future scars if nothing else. I wanted to add this in here as full disclosure. It *seems* that my scars are improving due to the serrapeptase, but the additional measures that I am taking may also be playing a role in their improvement.
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